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XELTABİN 500 mg film-coated tablet Taken orally.
Each tablet contains 500 mg of capecitabine.
Anhydrous lactose, microcrystalline cellulose, croscarmellose sodium, hypromellose, magnesium stearate, titanium dioxide (E171), yellow iron oxide (El72), red iron oxide (El72), talc
2.What is XELTABIN and what is it used for?
XELTABIN belongs to a group of drugs called "Cytostatic agents" that stop the growth of cancer cells.
Xeloda contains 500 mg capecitabine, which is not itself a cytotoxic agent (kills the cell or stops its functions). After absorption by the body, it turns into a cytotoxic substance inside the tumor cell.
XELTABIN 500 mg printed “500” on one side and flat on the other side; It is a peach colored, oblong, biconvex film-coated tablet and each box contains 120 tablets.
XELTABIN is used in the treatment of cancers of the large intestine, the end of the large intestine (rectum), stomach or breast cancers. In addition, XELTABIN can be prescribed by your doctor after complete removal of the tumor by surgery to prevent recurrence of colon cancer.
3.How to use XELTABIN?
Your doctor will prescribe a dosage and treatment regimen that is right for you. The dose of XELTABIN is adjusted according to the body surface area. This is calculated from your height and weight. The starting dose for adults is 1250 mg / m2 administered twice daily (morning and evening). There are two examples here: a person with a body weight of 64 kg and a height of 1.64 m has a body surface area of 1.7 m2 and should take 4 tablets of 500 mg and 1 tablet of 150 mg twice a day. A person with a body weight of 80 kg and a height of 1.80 m has a body surface area of 2.00 m2 and should take 5 tablets of 500 mg twice a day.
XELTABIN tablets are usually taken for 14 days, followed by a 7-day rest period. This 21 day period is one treatment cycle.
In combination with other agents, the initial dose for adults may be less than 1250 mg / m2 and you may need to take the tablets over a different time period (eg every day without a rest period).
Your doctor will tell you how much dose you need, when to take it and for how long.
Your doctor may want you to take a combination of 150 mg and 500 mg tablets for each dose.
• For morning and evening doses, take the combination tablets as prescribed by your doctor.
Take the tablets within 30 minutes after meals (breakfast and dinner).
4. What are the possible side effects?
Like all medicines, people who are sensitive to the substances contained in XELTABIN may have side effects.
If any of the following occur, stop using XELTABIN and IMMEDIATELY inform your doctor or go to the nearest emergency department.
• Diarrhea: If your bowel emptying increases 4 or more compared to your normal daily bowel emptying or if you have diarrhea at night.
• Vomiting: If you vomit more than once in a 24-hour time period
• Nausea: If your appetite is reduced or the amount of food you eat every day is less than normal
Stomatitis: If you have pain, redness, swelling and sores in your mouth and / or throat
Hand and foot skin reactions: if you have pain, swelling and / or pain in your hands and / or feet.
there is a rash or tingling
Fever: if your body temperature is 38 ° C or higher
• Infection: If you have signs of infection caused by bacteria or viruses or other organisms
Chest pain: If you experience pain in the center of your chest, especially during exercise
Steven-Johnson syndrome: If you observe painful, red or purplish rash that tends to spread and blister on your body and / or new lesions begin to appear in the mucous layer (e.g. mouth and tongue), especially before light sensitivity, respiratory system infection ( eg bronchitis) and / or fever.
If noticed early, these side effects will resolve within 2-3 days after cessation of treatment.
If side effects persist, consult your doctor. Your doctor will advise you on a low dose of the drug.
It may prompt you to start over.
In addition to the above, the very common (more than 1 in 10 patients) side effects of XELTABIN when used alone:
Rash, dry or itchy skin
Loss of appetite (anorexia)
These side effects can become severe, so it is very important that you always contact your doctor immediately if a side effect begins to occur. Your doctor may direct you to reduce your dose or temporarily take a break from XELTABIN. This makes the side effects less likely to persist or become severe.
All these are serious side effects. If you have one of these, it means you have a serious allergy to XELTABIN. You may need urgent medical attention or hospitalization.